The State Department said the US this week made the determination that Russian Federation had used the Novichok nerve agent to poison Sergei Skripal and his daughter, Yulia, and that sanctions would follow.
The Skripals fell unconscious on a park bench in Salisbury, Wilts, on March 4 after being exposed to a military-grade nerve agent determined to be Novichok.
The sanctions will take effect on August 22, the State Department noted.
A senior State Department official said it had notified the Kremlin of the sanctions earlier in the day.
There would, however, be exemptions for space flight activities, government space cooperation, and areas covering commercial passenger aviation safety, which would be reviewed on a case by case basis, the official added.
A US State Department official said the action is aimed at punishing Russian government for having "used chemical or biological weapons in violation of global law".
Acting in tandem with governments in Europe, the United States expelled 60 Russian diplomats it said were spies several weeks later.
Russia's embassy in London said they had not received any extradition requests over allegations any of its citizens were involved in the novichok poisonings.
Three months later a British woman, Dawn Sturgess, died after being poisoned by novichok in a...
The sanctions are mandated under the Chemical and Biological Weapons and Warfare Elimination Act of 1991, which says the U.S. president shall tighten the penalties within 90 days unless Moscow provides "reliable assurances" that it no longer engages in such activities, and allows on-site inspections by United Nations observers.
President Trump met with Putin at a summit in July.
The White House did not immediately send out a statement on the sanctions.
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