Switzerland's Roger Federer heads to the exit at Wimbledon after losing for the fifth time in his career with a two-set lead. We thought he could lose to maybe somebody else, but not necessarily Anderson, who hasn't had huge success coming into this tournament.
On Wednesday, he went up two sets to love against Kevin Anderson, a formidable but clearly overmatched player.
This exchange was made possible after Roger Federer took to channelling his inner Sachin Tendulkar while playing his Round of 16 match on Centre Court at the All England Club on "Manic" Monday. But that turned out to be the least of his worries.
Djokovic looked in control in the first set.
Defending champion Roger Federer suffered the most shocking defeat of the tournament so far as he was knocked out by big-serving South African Kevin Anderson.
Federer couldn't convert a break point at 3-4 and as the final set headed into extra time a lone voice in the crowd, mindful of England's imminent World Cup semi-final against Croatia, shouted out "Hurry up I need to watch the football". With South African Kevin Anderson taking nearly 3-1/2 hours to tame French showman Gael Monfils in a four-set thriller in the previous match, Djokovic was left with about two hours of daylight to complete his match against Karen Khachanov if wanted to avoid coming back on Tuesday again. Anderson and Federer are knotted at 3-3 in the final set.
Deploying his huge serve to lethal effect, Anderson roared back to leave the champion's title bid in tatters thanks to a barrage of 28 aces and 65 winners.
The final set lasted 90 minutes, and it was captivating stuff.
There was still the small matter of holding serve but a 28th ace helped settle Anderson's nerves and be brought up match point with a massive forehand before completing a remarkable victory with a first serve that Federer could not handle.
Then in the 23rd game, at 11-all, 30-30 Federer blinked, sending down a double-fault and then drove a forehand into the net to allow his giant opponent to serve for a place in the semifinals.
The level of Djokovic's opposition is certain to increase in the semi-finals, however, with either second-seed Nadal or fifth-seed Del Potro promising to offer the Serb the stiffest challenge of his Wimbledon run.
Federer had been pursuing a 13th Wimbledon semi-final and a 44th appearance in the last four of a grand slam.
"I'm not quite sure what to say, I had to try my best to keep fighting", Anderson told the BBC.
'I think there was a real hope his elbow could heal naturally, holistically.
"Beating Roger Federer at Wimbledon will be one I remember. I just kept telling myself this will be my day".
But Anderson was just getting started.
The Ottawa native and partner Yifan Xu of China, the tournament's sixth seeds, defeated the unseeded pair of Bethaine Mattek-Sands of the US, and Lucie Safarova of the Czech Republic 5-7, 6-4, 6-2 in a quarter-final on Wednesday. He won the Australian Open for the sixth time earlier this year.
He said: "I just asked the chair umpire how did I deserve that warning?" I think his learning curves could be quicker but they have to be his.
He then let rip at Ramos for failing to sanction Nishikori for a similar act in the fourth set.
"He claims that he didn't see what Nishikori has done, but apparently he always sees what I do".
"That was very important", he added. "I played only once in first four matches on Centre Court".
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