Ireland have relegated Johnny Sexton to the bench in making six changes for Saturday's first Test against Australia at Brisbane's Suncorp Stadium.
Australia had been preparing all week for the kicking and playmaking threat the 73-Test five-eighth would bring, but Schmidt made a decision to try to freshen him up for the rest of the three-Test series at the end of a long, taxing season.
Peter O'Mahony will captain the side in the absence of Rory Best and is joined by fellow Munsterman CJ Stander in the back row alongside Jordi Murphy.
CJ Stander is one of six Munster players named in the Ireland team that takes on Australia.
It could also represent a possible first viewing of a half-back partnership with Conor Murray, just nine days after Carbery announced he was leaving Leinster and joining Munster for next season in a bid to get more game time at number 10.
The Six Nations back three of Rob Kearney, Keith Earls and Jacob Stockdale remains in situ, with Bundee Aki again the man in possession of the 12 jersey. Robbie Henshaw and Bundee Aki are named in midfield as the two starting centres.
Munster-bound Joey Carbery comes in for British and Irish Lions outside-half Sexton for Ireland's first game since beating England in March to win the Grand Slam.
The frontrow has a whole new look to it, with Jack McGrath, Rob Herring and John Ryan selected at the coal face, with Iain Henderson and James Ryan the preferred pairing in the second row.
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