Still, buoyed by a boisterous Grandstand crowd chanting "Ole!" and his nickname, "delPo", he never gave in or gave up.
Rublev defeated No. 9 Goffin 7-5, 7-6, 6-3 in the Round of 16, after his 7-5, 7-6, 6-3, win over Dimitrov.
"I feel he had some problem with the knee then I feel a little bit more relaxed because I know now it just depends on me that if I play good I am going to win this match and this is what happened".
"I was sick the last two days", del Potro admitted after the match.
Nadal has practiced with Rublev in Majorca, describing him as a "great guy", but he did not accept that the teenager would be free of pressure when they meet. He was 2-5 down in the final set before coming back to win. After the match, he admitted he was getting a massage on his bottom.
Del Potro, the 2009 champion at Flushing Meadows, dropped the opening two sets of the fourth-round match. The ensuing tiebreaker was dominated by del Potro, who closed it with a booming cross-court forehand victor on the run.
Del Potro has a lot on the line Monday in a tough matchup against No. 6 seed Dominic Thiem of Austria.
Here's how close it was: Thiem actually won more points, 141-139.
If Federer's back isn't 100 percent, he could have his hands full with del Potro. He joked that he thought he should get a trophy just for winning this one.
Russia's Daria Kasatkina reached the last 16 of a major for the first time by seeing off French Open champion Jelena Ostapenko, the 12th seed, 6-3, 6-2.
Pliskova won 22 of 24 points on her first serve, broke Brady's serve six times and advanced to face No. 20 CoCo Vandeweghe, who beat Lucie Safarova 6-4, 7-6 (2) to become the third American into the women's quarterfinals. Federer won both the Australian Open and Wimbledon this season, and could face Nadal in the semifinals if they both make it that far.
"I really wanted to get another chance after being down match point in the last match", she said.
That was the first time in the 36-year-old Federer's career that he opened a Grand Slam tournament with two consecutive matches that lasted five sets.
Rafael Nadal returns a shot against Alexandr Dolgopolov during their fourth-round men's singles match at the US Open on September 4, 2017, at the USTA Billie Jean King National Tennis Center in Flushing.
"Every victory, every set that you win is more confidence". Even when I was eight years old, I was not very happy when my birthday was to be nine.
Not long after Nadal spoke, 19-time Grand Slam champ and No. 3 seed Federer disposed of Philip Kohlschreiber, the 33rd seed from Germany, winning 6-4, 6-2, 7-5 in 1 hour and 49 minutes.
Another American advanced when No. 20 seed CoCo Vandeweghe outlasted No. 10 Agnieszka Radwanska of Poland 7-5, 4-6, 6-4, and 15th-seeded Madison Keys hoped to join them later when she faced No. 17 Elena Vesnina of Russian Federation.
Women's top seed Karolina Pliskova saved a match point to defeat China's Zhang Shuai, hanging on to her World No 1 spot in the process.
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